Sentence examples for at a given dose from inspiring English sources

High antibody affinity at a given dose tends to decrease antibody percolation or penetration to the tumor because the high affinity binding to the edge of the tumor leads to fewer free antibody molecules.

Even for QSAR models which are typically classifiers, such as those used to predict carcinogenicity, it may be more appropriate and useful to have a quantitative evaluation of the potency, because if the chemical is carcinogenic then it is important to be able to evaluate the risk at a given dose level.

Therefore, we hypothesize that scheduling radioimmunotherapy 24 hours after chemotherapy improves the therapeutic ratio, and hence the clinical utility, of La-targeted chemo-radioimmunotherapy because the therapeutic ratio of any treatment will be improved by reducing its toxicity and/or increasing its efficacy at a given dose.

If ⩾2 patients experienced DLT at a given dose level, then dose escalation ended.

If no DLT was observed at a given dose level, three patients were enrolled at the next dose level.

If two patients at a given dose level developed dose-limiting toxicities, dose escalation was to be stopped.

If ⩽2 patients out of six patients experienced a DLT at a given dose level, escalation proceeded.

S is the surviving fraction at a given dose D. This calculation takes into account the mock-irradiated condition.

For the two tests at a given dose of cocaine, rats received pretreatment with vehicle (1 mL/kg, s.c).

If one of the three patients at a given dose had any dose-limiting toxicity (DLT), three other patients were assigned to receive the same dose.

However, if three or more patients experienced DLT at a given dose level, then the previous dose level was considered as the maximum tolerated dose.