Your English writing platform
Discover LudwigSuggestions(2)
Exact(2)
However, this effect can be completely masked by interacting genetic variants at a distant locus elsewhere in the genome [ 24].
In M19-40 this gene was found within the cluster while in UAH-SP71 this gene appeared at a distant locus in the genome.
Similar(58)
The precursor then duplicated to a distant locus.
These studies showed that transcript abundance was highly heritable and could be linked to either a local locus (cis-eQTL) or a distant locus (trans-eQTL).
Among the six bacteria screened, a partial operon was found only in E. coli, where the first three coding sequences had strong homologues, but the fourth gene encoding for the outer membrane efflux protein exhibited a homologue at a more distant locus.
Alternatively, even if similar selection goals might have driven to fixation the same variant in all the breeds compared, different SNP alleles might still be associated to it at more distant loci.
The longest composite repeats are 518-bp long and are present at two distant loci.
Less clear is whether intergenic lncRNAs commonly regulate transcription by modulating chromatin at genomically distant loci.
Furthermore, many miRNAs have seed family members encoded at multiple distant loci, which requires that multiple genes have to be simultaneously knocked-out to obtain full ablation and avoid gene compensations based on functional redundancy.
The transcripts and small RNA fragments identified at the D4Z4 repeats might be associated with local chromatin silencing, chromatin silencing at distant loci, or might target RNA from other loci.
Moreover, a single sponge transgene allows the simultaneous silencing of 'seed' sequence redundant microRNAs encoded at distant loci.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com