Your English writing platform
Discover LudwigExact(1)
An important characteristic of 3-D similarity methods, compared to 2-D similarity methods, is that 3-D similarity methods are applied at a conformer level, not at a compound level, to enable consideration of various distinct molecular conformations in 3-D space that may be biologically relevant.
Similar(59)
However, a small-scale assessment at Dundee (R. Brenk, personal communication, details to be published elsewhere) of libraries from five different groups revealed a large overlap at the core fragment level and minimal overlap at the compound level.
Queries were done at the compound level with particular sources or subsets selected via the "Limits" tab.
When these are collapsed at the compound level, 80% of the compounds are potent at less than 10 μM in at least one assay.
In this way, the model can refine the information in the noisy observations first at the compound level and then at the compound group level.
Proportions and 95% CIs were calculated, controlling for correlation at the compound level, because more than one child may have been surveyed from the same compound.
The best recognition rate obtained was 71.4 % at compound level 4.
Again, it is not possible to explore household factors related to the observed clustering (despite its obvious utility) because geographic information system data are only available for the centroids of the villages and at compound levels in the large villages, where a compound is made up on average of four households.
In the case of tetrachloroethylene exposure, both trichloroethanol and trichloroacetic acid levels, and consequently the total trichloro compound level, reach a plateau at tetrachloroethylene level well below 100 ppm.
Genetic structure was analyzed at the community and house compound levels.
Terminal plasma compound levels at the highest dose tested were 12.3 μM, a 17-fold multiple over the cellular IC50 for inhibition of Notch signaling.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com