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The median, 97.5th percentile, and 99.5th percentile of the asymmetry value of the VCDR were 0.05, 0.17, and 0.24, respectively.
The 97.5th and 99.5th percentiles of the VCDR on the left or right eye and those for the asymmetry value of the VCDR were used as the cutoff value for category 1 and category 2 glaucoma diagnoses, respectively.
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The average leakage current under negative formation (NF) is 229.7 pA at a read voltage (Vread) of -2.0 V, while it is 673.3 pA under PF at a Vread of +2.0 V. Asymmetry values of the leakage currents under NF and PF polarities are quite reasonable due to the different work function (Φm) values of IrOx [ Φm IrOx ≈ 5.2 eV [14], and of W [ Φm)W ≈ 4.3-4.91 eV [29]] electrodes.
This was done for both the variation among individuals (means of both sides for size and shape) as well as for FA (signed asymmetry values of size and shape).
Sequence asymmetry values of dinucleotide counts surrounding a representative TSS: The respective numbers of dinucleotide content (AA or TT denoted by AA_TT, CC or GG by CC_GG) and single nucleotide content (A, C, G, T, A or T represented by A_T, C or G by C_T) were counted 500 bp upstream and downstream of each representative TSS.
The significance of asymmetry values for each pattern was analyzed using raw data (Student's t tests of the mean relative to 0).
The asymmetry value at the beginning of treatment.
Computer experiments (see Figure 4) showed that a sharp decrease in the accuracy and confidence of global alignments takes place close to the asymmetry value c which is the root of equation (3) D g l o b (c ) = D r a n d (here the length of random sequences is L ker+L con).
(A low asymmetry value generally signifies axial symmetry and a high asymmetry value denotes otherwise).
In addition we calculated the crude hemispheric asymmetry (absolute value of the difference between right side and left side: ABS (right-left) for all amplitude and peak frequency measures.
Using the L ker, PAM, r values, the above stated allows us to roughly determine the range of asymmetry values c at which the quality of global alignment decreases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com