Exact(25)
An implicit mutation typically follows an explicit mutation that causes the asymmetrical division of a copied genome, where one of the asymmetric copies can then faithfully and successfully self-replicate [ 22].
It's asymmetrical division in cancer stem cells, which is a very new field.
Wang, J. et al. Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages.
But these daughters grow more slowly than the favoured daughters of unequal divisions, because their resources have to be divided between maintenance and reproduction.When Dr Watve ran the model, he discovered that the main determinant of whether symmetrical or asymmetrical division was favoured was the amount of food around.
An asymmetrical division of type A undifferentiated spermatogonia was suggested previously in zebrafish based on morphological evidence [2].
We speculate that the asymmetrical division of Aund might prevent its exhaustion during spermatogenesis, maintaining, therefore, a subset of immature Aund.
Similar(35)
In such cases, one of the daughters is identical to the original stem cell, while the other takes on new characteristics and can then differentiate into whatever cell type the tissue it inhabits requires.During asymmetrical divisions, some stem cells take an extra step to preserve the integrity of their DNA.
(By contrast, the cells that comprise the bulk of most tumours lack these surface proteins and are poor at creating new tumours).Dr Ryan, Dr Pine and Dr Harris reasoned that if such cells really are stem cells then they should be able to undergo both symmetrical and asymmetrical divisions, just like the stem cells in healthy tissue.
AtSCR is involved in the asymmetrical divisions that generate separate endodermal and cortical cell lineages.
In addition, the Δga5dh cells exhibited severe division defects, including abnormal septum position (Fig. 4A) and asymmetrical divisions (Fig. 4B).
An anticlinal division generates the metaphloem cell (B2 and B3); next, the metaphloem sister cells undergoes two successive asymmetrical divisions and the small cells form the companion cells (B4 and B5) surrounding a single protophloem cell.
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Justyna Jupowicz-Kozak
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