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Asymmetric cell division is also influenced by the extracellular environment.
Fig. 1 A model for self-renewal of NSCs and CSCs through asymmetric cell division.
Generally, asymmetric cell division is regulated by two types of mechanisms, intrinsic and extrinsic.
This mimics asymmetric cell division.
AGS3 also functions in asymmetric cell fate by controlling mitotic spindle orientation during brain development [26].
Interestingly, these cells expressed CD133 and showed asymmetric cell division [28], [29].
Cell polarization is essential for processes such as cell migration and asymmetric cell division.
Similar findings of asymmetric cell division were observed in doxorubicin-treated LA-N-5 cultures.
NEUROG2 may further be involved in the asymmetric cell divisions of progenitor cells [19].
One mechanism by which cell fate diversity can be achieved is asymmetric cell division.
Asymmetric cell division generates daughter cells containing different developmental determinants [5].
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