Will the Twins, without the astute Tom Kelly as their manager, be able to avert contraction?
The Sackler School of Medicine at Tel Aviv University will not be the same without Saul Farber's astute direction.
His leadership was astute and his demeanour aggressive without quite crossing the line – exactly what you need for compelling theatre and fantastic cricket.
But VanderPlas's astute observations merit serious consideration because, without "changes in the culture of academia itself" like those he suggests, he fears that "the progress of scientific research will be severeley [sic] handicapped in the coming years".
Without consulting the diplomatically astute Calvert, the prince and the duke travelled to Spain to negotiate the Spanish marriage for themselves, with disastrous results.
Playing with an astute simplicity, the drummer Brian Chase was almost never glimpsed without a smile on his lips over the course of this 90-minute show.
"Without anyone being spectacular, everyone was really astute at their job.
"Without being spectacular, I thought we were really astute," said the Hull coach, Lee Radford.
"The Allams are very astute businessmen and they don't put money into something without very careful consideration," said Hudgell.
