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Interestingly, in some studies, the association between obesity and asthma was found to be stronger in non-atopic than atopic children [20,21], and the association between BMI and asthma seems to be stronger among girls than boys [1,22-24].
In a recent study of 295 Korean children with atopy, the rs10399805 CHI3L1 promoter variant was associated with increased risk of atopy whereas an association between rs4950928 and atopy was not seen and in general no association between variations of CHI3L1 and asthma was found [7].
No difference in frequency of asthma was found.
However, no significant association between genotype and allele frequencies between this SNP and asthma was found.
Asthma was found in 50%to60%0% of the children with GER [ 5].
A strong positive family history of asthma was found in the case group (40.1%) in comparison with controls (6.7%).
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Could nephew Yannis, about to begin his military service and suffering from asthma, be found a safe post at the defence ministry in Athens?
In fact, obese children with asthma were found to have significantly higher Th1 and lower Th2 responses to specific stimuli compared with non-obese asthmatic children [61].
No associations between traffic exposure at school and wheeze or asthma were found.
Within western societies furthermore, lower levels of asthma were found in families with traditional lifestyles [ 47, 48] and higher levels of asthma were found among obese or less physically fit children and adults [ 49- 51].
6 A higher prevalence of asthma is found among those suffering from persistent and more severe rhinitis.
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