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Results: Only 5% of patients treated with FP100/salmeterol withdrew because of worsening asthma in the first 12 weeks; this compared with 7% in the FP250 group.
The objective of this cohort study was to determine if complications of pregnancy and labor, characteristics at birth, and exposure to infections influence the incidence of asthma in the first 6 years of life.
Several candidate genes control asthma-related immune responses, but researchers don't know which genes make people more likely to come down with asthma in the first place.
The age of the weight gain may play a role, as pronounced weight gain early in life was identified as a risk factor for developing asthma in the first 6 years of age [35].
Neil Churchill, chief executive of Asthma UK, said two-thirds of people with asthma found traffic pollution made their condition worse, but it had also been found that traffic pollution played a part in causing asthma in the first place.
Almost 6% of children had suffered from all the 3 single phenotypes (ever bronchiolitis, ever wheezing and ever doctor-diagnosed asthma) in the first year of life.
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As such, the prevalence of diagnosed asthma in the second study remained statistically the same at 15%, however the prevalence of possible undiagnosed asthma increased over six-fold to 18.6%.
Carroll et al. described the association between full-term children who had outpatient visits or hospitalizations for bronchiolitis in infancy and asthma in the sixth year of life [ 13].
An asthma diagnosis is often preceded by asthma symptoms in the first years of life.
Furthermore, we did not consider prescriptions before 6 years of age, which we believe is a strength because many children are prescribed asthma medications in the first years of life, although they do not necessarily develop clinical asthma (Ingvardsen et al. 2000).
We are pleased to see significant health benefits from the U.S. Environmental Protection Agency's (EPA) proposed limits on carbon pollution from power plants, which would reduce the burden of air pollution in America, prevent up to 4,000 premature deaths and 100,000 asthma attacks in the first year they are in place, and prevent up to 6,600 premature deaths and 150,000 asthma attacks in 2030.
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