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> Twenty-three models for predicting asthma development have been developed for the general child population.
As mentioned in the introduction, predictive models for asthma development in children are developed to facilitate asthma diagnosis and prevention.
Six models for predicting asthma development in children have been developed for the primary care setting.
To facilitate asthma diagnosis and prevention, researchers have developed multiple models for predicting asthma development in children.
Allergic rhinoconjunctivitis is a risk factor for asthma development.
Epigenetic regulation is an important mechanism by which environmental factors might interact with genes involved in allergy and asthma development.
Thus, Notch signaling plays a key role in maintenance of healthy epithelial barrier integrity and may decrease the risk of AD-associated MPD or asthma development.
Human rhinovirus infection (HRVI) plays an important role in asthma exacerbations and is thought to be involved in the asthma development during childhood.
Th9 cells, which mainly produce IL-9 form another T cell subset that has recently been described to drive asthma development.
Only one study has addressed the putative involvement of the immunoproteasomes in asthma development using knockout mice for the immunoproteasome subunit LMP7.
In humans, this smoking grandparent effect on asthma development in the offspring was also reported [17] but no epigenetic analyses were available in that study at the time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com