As mentioned previously, the perimeter trace of the LigandTracer® was used to assure cell viability and attachment.
Appropriate patterns of DNA methylation and histone modifications are required to assure cell identity, and their deregulation can contribute to human diseases, such as cancer.
Micro-aeration was considered as an important condition for the fermentation process, since yeasts require low amounts of oxygen for synthesizing some essential lipids to assure cell membrane integrity (Mauricio et al. 1997).
In this matter, the activation of RAS-Erk1/2 pathway would engage biochemical mechanisms to coordinate cell growth and division to assure cell proliferation.
Since the activation of AMPK-TSC1/TSC2 pathway by LKB1 controls energy metabolism and protein synthesis, we examined whether the growth factor treatment leads to LKB1-AMPK dissociation, providing a mechanism that would assure cell growth upon a mitogenic stimulus and resistance to energy stress conditions.
Centers located in Europe and Canada received cells shipped in dry shippers filled with sufficient liquid nitrogen to assure cell integrity for up to 7 days.
Depletion of USP1 in cells derived from FA patients resulted in decreased CHK1 levels and phosphorylation, suggesting that mono-Ub-FANCD2 is not the only USP1 target involved in CHK1 regulation and that the germline-derived inactivation of the FANC pathway in FA patient-derived cells uncovered or selected other pathways to compensate for their intrinsic deficiency and assure cell survival.
Assuring cell adhesion to an underlying biomaterial surface under blood flow is vital to functional vascular grafts design.
The use of biomaterials as scaffolds for transplantation assured cell delivery and supported cell behavior toward the chondrocytic phenotype to provide a chondrogenic potential to regenerate articular cartilage.
As well as native tissues that are composed of nanosized biomolecules and of cells that interact with the ECM, nanomaterials such as nanoparticles [22, 23], nanotubes [24, 25], nanofibers [26, 27, 28, 29] and other nanostructured fabricated devices with features smaller than 500 nm, can closely mimic native biological system by assuring cell growth and tissue regeneration [14, 30].
