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In a 1991 nude dancing case, he was willing simply to make the assumption of harm.
Comparing these studies side by side may provide insight into how the assumption or lack of assumption of harm affects the estimated benefit of the intervention.
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Judge Sweet found that Grape Finds, which opened Dec. 3 in the capital's Dupont Circle area, had "copied protectable elements" of Best Cellars's distinctive "trade dress" -- that is, had appropriated the look and feel of Best Cellars in a way that might cause "numerous ordinarily prudent customers" in Grape Finds to confuse it with Best Cellars, creating an assumption of "irreparable harm".
Our assumption of the real harm rates in different patient populations was based on previous research and covered a tenfold range from two to 20 incidents per 100 patients per year [ 1, 17, 18].
Extrapolation required an assumption of constant benefits and harms from additional rounds of screening.
If we make these assumptions, we can then use this notion of harm to explicate the claim "by bringing a person into existence we can cause harm to this person" without having to confront the peculiar ethical difficulties discussed in the previous paragraphs.
In other words, Vietnamese traditional alcohol comes with Vietnamese traditional assumptions that curb its use and lower the risk of harm.
Detection of real intervention effects requires adequate control of any bias that may distort the effect so as to ensure that there is no false assumption of effectiveness and lack of possible harm.
"Evidence of harm"?
Little chance of harm there.
Out of danger, out of harm.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com