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Carbon emission reduction schemes by improving residential building energy performance are often developed and assessed upon the assumption of current or stationary climates.
However, recent advances in post-genomic biology are indicating that polypharmacology may be a necessary trait for the efficacy of many drugs, therefore questioning the 'one drug, one target' assumption of current rational drug design.
Regarding the current density of discrete points as unknown parameters, the vector expression of K Bn, which is the coefficient of K, will be obtained by the series formula of Bessel function according to the linear distribution assumption of current between the adjacent discrete points.
As both anaemia prevalence and colorectal cancer incidence rise with age, it is possible that the relative risk of colorectal cancer with anaemia is largely independent of age; this is a tacit assumption of current guidance.
An underlying assumption of current approaches is that DNA-binding proteins, such as transcription factors, contain sequence-specific, DNA binding domains that target a cluster of cis-acting DNA elements sharing certain sequence features.
A core assumption of current toxicologic procedures used to establish health standards for chemical exposures is that testing the safety of chemicals at high doses can be used to predict the effects of low-dose exposures, such as those common in the general population.
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This is represented with high order Taylor maps which can be potentially used for the implementation of innovative algorithms for risk assessment, avoiding the main assumptions of current approaches.
One of the main assumptions of current GWAS is that common diseases are caused by at least a few common genetic variants of relatively large effect (the common disease, common variant [CDCV] hypothesis).
The company said it "intends to make absolutely clear that the proposed alliance will not entail the assumption of any current or future indebtedness to Chrysler".
The Italian automaker said earlier this month that it "intends to make absolutely clear that the proposed alliance will not entail the assumption of any current or future indebtedness to Chrysler".
The issues above are important because if present-day trait-climate relations do not have the expected adaptive explanation, or were not constant over evolutionary time, then the core assumption of the current uniformitarian approach would not be valid (i.e., leaf physiognomy-climate relations may have differed in the past).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com