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Participants were not on antidementia drug therapy (cholinesterase inhibitors or memantine) for the presence of prescription contraindications (ie, heart arrhythmia, previous episodes of syncope, severity of cognitive impairment above the threshold required from the Italian health regulatory system) or no guarantee of drug assumption compliance.
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One problematic assumption concerned compliance.
We argue that the clients' complaints have the potential to challenge an assumption of compliance embodied in the staff members' conversational practices and that an orientation to this potential is reflected in the staff members' hostile reception of those complaints.
13 Thirdly, we needed to make assumptions that compliance with scheduled clinic visits was independent of the risk of the end point to justify our statistical approach.
The overall findings of the evaluation were sensitive to assumptions about compliance with follow-up visits to the extent that they altered the relative ranking of the strategies.
However, the study considered only men, included no costs for the screening programme (except for a blood test and consultation) and made unrealistic assumptions regarding compliance with treatment.
Although studies that involved a purely modeling approach often suggested significant cost reductions, they based these estimates on unrealistic assumptions of compliance or health worker behavior change and are consequently assigned a low level of evidence.
When the assumption of 85% compliance was dropped (ie, assumed 100% compliance), the ICER increased to £15,695.
Given μ ∈ D, evaluate (recalling the compliance assumption) s N N = f ( u N N , (22).
If drivers are under the assumption that the compliance rate among other drivers is too low, they guard themselves from exploitation by refusing to comply themselves.
Although this latter result depends critically on the compliance assumption, extension via adjoint approximations to the non-compliant case is possible; we discuss this further in Section 7. We now consider the discrete equations associated with the Galerkin approximation (23).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com