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The most conservative estimate for the FDR is found by assuming that the tests are independent and that all the N null hypotheses are true, in which case the expected number of false positives is the number of tests times the chosen level of significance.
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In most of these projects, an incremental approach to revision of the OECD guidelines has been applied, assuming that the test methods, developed for soluble chemicals, can be made applicable to nanomaterials through methodological adaptation.
Assuming that the test frame x t is labeled by a GMM m 1 x t and the training frame y t ' is labeled by a GMM m 1 y t '.
Incidence of HIV infection was firstly estimated using original data, assuming that the testing history data and the AI results are missing completely at random.
Assuming that the test-statistics underlying the two-sample t-test were independent across genes and using the estimator of Schweder and Spjøtvoll [ 21], the number of genes with unchanged ratios was of the order 64%.
Had we been able to take into account all nonpalpable lesions, implementation of LCNB would have resulted in a further decrease of costs and an increase in life-years lost, assuming that the test characteristics of LCNB are similar for nonpalpable lesions detected within and outside the breast cancer-screening programme.
The model assumes that the tests perform the same in all the sub-populations (i.e. Divisions) and that only the true prevalence differs.
Standard adjustments for multiple hypothesis testing, such as the Bonferroni correction, are too conservative, as they assume that the tests are independent.
It was assumed that the tests had been carried out when there was a record of any serological result relating to HIV.
For simplicity, we assume that the test perfectly classifies the patients: e = s = 1.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com