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In a recent study Sguanci and coworkers [ 16] investigate the changing environment by assuming that the susceptibility of target cells (or infectivity of viruses) increases in favour of X4 cells as soon as these emerge in an auto-catalytic fashion, however, staying with the assumption that the initial infection is with R5 virus only.
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Assume that the fitness cost of carrying a disease allele is proportional to the degree to which it increases disease susceptibility.
In these simulations, we assume
Based on these observations, we assume that the susceptibility to impaired vision is mediated by the interaction of the mutated Myo15 gene, the genetic background and unknown environmental factors.
'Negative frequency-dependent selection' explains the persistence only when the fitness of the affected individuals increases as the prevalence in the general population decreases, which seems not to be the case with SZ. Heterozygotee advantage' assumes that the susceptibility alleles increase the fitness of the unaffected gene carriers, thereby sustaining the gene frequencies.
We might assume that the susceptibility to bacteria was not the only limiting factor for cv.
We assume that the CARS susceptibility p measured at any voxel p of the image is given by the weighted sum of the susceptibilities { k } of chemical components numbered by k with non-negative relative volume concentrations c p { k }, such that 11where K is the number of relevant components.
We therefore assumed that the increased susceptibility of HUVECs to activated NK cells was most likely due to the absence of the inhibitory ligand HLA-E.
Because vitamin E levels were not different between macrosomic and control rats and were not affected by the EPAX diet, we assumed that the increased susceptibility of VLDL-LDL to oxidation in macrosomic rats fed with this diet was due to their enhanced DHA and EPA percentages.
We assumed that the 2009 H1N1 susceptibility of individuals with prior exposure to sH1N1 is reduced due to T-cell cross-reactivity of conserved epitopes (by a factor δ p ), but remains unchanged for those who had no prior exposure to sH1N1 (see [ 11, 12]).
Assuming that the frequency of coitus is independent of age, the probability of infection per partnership can be taken as a proxy for susceptibility with age.
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