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Modeling of these transitions often assumes system bistability, in which cells can be resting in one of two stable states.
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The proposed framework extends both classical reliability and methods that assume system degradation profiles.
These issues are considered by studying the performance of the assumed system through analytical results when they are derivable and through simulation results.
hfill end{gathered} (9 Each quantity x i is subjected to a standard uncertainty deriving from measurement errors or by natural tolerances when assuming system parameters as constants.
When the assumed system model is exposed to changes, A and B also need to be updated.
Compared with ANN, the new model is generated without assuming system structure or parameters a prior, thus no parameters needs to be initialized, which can help circumvent the bottleneck of estimating all initial parameters.
Therefore, architecture and systems engineering must assume systems or components have been compromised and missions and business functions must continue to operate despite compromises.
Instead, it assumes the system will eventually be compromised and therefore refreshes the system non-deterministically.
The disadvantage, however, is that it assumes the system is homogeneous which is not the case in our study.
The Michaelis-Menten model also assumes the system is homogeneous and ignores the intracellular protein transport process.
Therefore we consider the dominant system, assuming that the system contains only the links in.
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