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"Without unequivocal GMC and NICE support, ophthalmologists are understandably concerned that they may be assuming unacceptable personal liability by using an unlicensed drug when a licensed alternative exists," they write.
There seems to be no reason to assume that GPs take unacceptable risks since medical factors are still taken into consideration.
The power properties of the applied 3+3 design are as follows: assuming an unacceptable high true DLT rate of 50% the probability to observe at least one DLT of three patients is given by 87.5%, the probability to observe at least two of six patients, which means no further dose escalation, is given by 89.1%.
If the RAC values are not exceeded in surface water, it can be assumed that no unacceptable effect on aquatic species will occur.
If a reduction of filtering efficiency exceeds 0.5 dB (in terms of PSNR and PSNR-HVS-M) or 0.005 (in terms of MSSIM), mixed noise parameters estimation is assumed to be unacceptable.
Given their long exposure to investigations of Senator Torricelli, he added: "A good number of New Jerseyans assume that something unacceptable has gone on.
It was assumed that repeating the ungrammatical or unacceptable sentence would help the students pay more attention.
The censor hadn't read it and assumed it was about an attractive black woman – a totally unacceptable notion at the time.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com