Sentence examples for assumed toxicity from inspiring English sources

For simplicity, we assumed toxicity was low at both dose levels again, and only considered efficacy.

The assumed toxicity concern associated with the ethylene sulfide byproduct has largely limited the advancement of SATE/DTE prodrugs into development, but it is commonly used in the in vitro studies to deliver phosph on)ates intracellularly.

In spite of its assumed toxicity, there has been considerable controversy about its long-term health effects [ 33, 34], and it has not been confirmed if paternal exposure to Agent Orange can affect gene expression during spermatogenesis [ 35].

The approach assumes toxicity is nondecreasing with dose and fits an isotonic regression to accumulated data.

This is counter to classical aposematic theory, which assumes toxicity from diet arises before signaling.

Therefore, it is important not to assume toxicity is negligible just because patients are slow to report problems.

Assuming toxicity of combined radioimmunotherapy being less severe than in radiochemotherapy as demonstrated by Bonner and co-workers [ 19], this may still be feasible following TPF induction.

The present study was designed to explain the differences in isoprene toxicity between mouse and rat based on the liver concentrations of the assumed toxic metabolite isoprene diepoxide.

We introduce a new design for dose-finding in the context of toxicity studies for which it is assumed that toxicity increases with dose.

Given that little toxicity was found in the phase I studies, we assumed low toxicity probabilities in our simulation scenarios, specifically, 0.15 at both dose levels.

In the base case, we assumed that toxicity secondary to HAART in the developing infant would not be enhanced by directly observed HAART.