For one thing, they assume everybody eligible would come.Nor has the government made much of an attempt to advertise the economic benefits of immigration for Hong Kong's greying population.
However, this implicitly assumes the eligible patient population to which information from a trial can be applied across a time horizon are independent of time for trial accrual, follow-up and analysis.
Assuming patients eligible for a phase II study of a new cytostatic agent have failed previous cancer treatment, their most recent prior time to progression interval, TTP1, is uncensored.
Assuming 1.25 eligible adolescents per parent (85% of whom would complete all four surveys), design effects totalling 1.20 from clustering and weighting, and an outcome correlation of 0.6 within participants from baseline to nine months, we calculated that we needed to enrol a total of 570 parents (with 712 corresponding adolescents).
Thus, for households where no contact was made, it was assumed that two eligible residents lived there.
The estimates of benefit may well be over estimates as we have assumed that all eligible patients are identified, treated and comply with treatment.
Patients in the HCC state were assumed to be eligible for liver transplant in the first 3 months of disease only.
In our model, it was assumed that all eligible individuals could be vaccinated or treated; however, the vaccination and diagnosis rates could be less than 100% and their relative values will influence the investment decision.
The base-case scenario assumed that all eligible patients were treated with peginterferon + ribavirin, and that 10% of the genotype 1 patients were treated with the most recent protease inhibitors (50% with telaprevir and 50% with boceprevir).
Within each supermarket, we identified the number of eligible ranges present and assumed that all six eligible meal types were available in both chilled and frozen versions within these ranges.
