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This requires a change in our original hypothesis (Gatenby and Gillies, 2004) which assumed central necrosis in DCIS was caused by limited glucose diffusion.
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In the novel "Wait Until Spring, Bandini," Colorado is home, and family matters assume central importance.
Churned out 200 years before Gutenberg, the books assume central importance when the caliph, by now retracting his open-mindedness, orders them to be burned.
There's always one moment, one telling event that will go on to assume central significance in an argument that encompasses the globe and decades of history.
Asia, as he correctly observes, is the key crucible of future conflict, with East Asia in particular set to assume central importance.
In earlier thinking about development, it was assumed that the market mechanisms of developed economies were so unreliable in developing economies that governments had to assume central responsibility for economic activity.
He writes:This sort of simplistic reasoning assumes central bankers only need to manage a single trade-off between the rate of consumer price inflation and the level of joblessness.
It added: "The supportive actions by central banks can be useful, but there are serious risks involved if governments, parliaments, public authorities, and the private sector assume central bank policies can substitute for the structural and other policies they should take themselves.
I'd say one of its chief difficulties in its first year has been shifting from the relentlessly controlling, on-message, no-drama, one-star-in-the-firmament message of a campaign to the different demands of the presidency, where the humanity of America's leader, his flesh-and-blood fallibility and impulses, assumes central importance.
A similar type of bias in assuming central control can be seen throughout the early history of science.
Dialog need not humiliate, assuming central government bigwigs maintain their dignity, planted safely behind the scenes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com