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For a long time hypoglycemia was assumed a major problem only in patients suffering from type 1 diabetes (2); however, there is increasing evidence that hypoglycemic episodes are a critical factor also in type 2 diabetes (3, 4).
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Ryan's players assumed a major shakeup was inevitable.
Effect of modified crops on the biological activity of the predation level of insect predators such as C. carnea is assumed to be a major problem.
"We have a major problem, and it's time to assume responsibility for our problem".
He offers these three tips in explaining those benefits: "Ask what problems your solution solves: Let's assume you are targeting writers and have determined that time management is a major problem for writers.
This is not a major problem if socialisation patterns are stable, but it is relevant to assume that such patterns develop during the acculturation process.
A major problem here is the large consumption of unrecorded alcohol (which we assume to be in the form of illegally-produced and artisanally-produced pot-still cachaça).
My first aim is to remind people that this is a major problem at home, and that a lot of prostitution is less voluntary than people usually assume.
A major problem of this model is that unrealistic enrichment of the solids at the interface as compared to the bulk concentration has to be assumed.
A major problem was parking.
"They are a major problem".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com