The phrase "assumed a clinically relevant" is correct and usable in written English.
It can be used in contexts related to medical or scientific discussions, particularly when discussing the significance of findings or conditions in a clinical setting.
Example: "The study assumed a clinically relevant threshold for the treatment's effectiveness."
Alternatives: "considered a clinically significant" or "deemed clinically important".
Sample size requirements were estimated assuming a clinically relevant mean difference between preoperative and postoperative HRQoL (PCS) score of 5 (SD 10).
Hence, using a 2-sided alpha of 0.05 and 225 patients per group, the trial has a 91% power to detect superiority of MRI referral over usual care assuming a clinically relevant difference of 15% in knee function.
Assuming a clinically relevant difference in CIN incidence of 20% and 60% CIN in the control group (worst case), 108 patients per group are required for the chi square test.
A sample size of 246 completed patients (123 per arm) would ensure 90% power with a one-sided significance level of 2.5% to declare superiority of vildagliptin 50 mg bid over placebo in HbA1c reduction from baseline after 24 weeks of treatment, assuming a clinically relevant difference of 0.5 absolute units between treatments and a standard deviation of 1.2%.
When patients at the follow-up consultation (by phone or in the office) reported that symptoms improved and no antibiotics had been prescribed to them since the first consultation we assumed that a clinically relevant pneumonia could be excluded with a high degree of certainty.
The baseline response rate on 5-FU alone was assumed to be 5%, and a clinically relevant response rate of 20% on 5-FU/gefitinib was defined.
The definition of a fully recovered patient was a NIHSS score of 0 or 1. Fifty-five perelativelative proportion of fully recovered patients was a clinically relevant effect, assuming an equal treatment effect as the potential competitor tissue plasminogen activator treatment.
Cutting non-compliance time in half (or more) was considered a clinically relevant endpoint that, assuming a power of 0.8 and a significance level of 0.05, would require 21 patients in each group to be adequately powered.
This discrepancy corresponded to 0.76 mSv (2.96 and 3.72 mSv from mice and humans, respectively) while assuming an injected activity of 200 MBq as a clinically relevant dose.
A 1 1 test:control recruitment rate was assumed and, given that no previous clinical trials had been conducted in canine EPI, a clinically relevant difference in efficacy between treatments of 40% was decided.
