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We assume that the exposure time to 1°C was simply too long in order to yield a measurable effect of a 1 hour exposure to different hardening temperatures.
In this scenario we assume that the exposure is not subject to confounding, i.e. β4 = 0.
We assume that the exposure and outcome are continuous; issues relating to binary outcomes are reserved for the discussion.
While individual exposures differ from the mean exposure in each city in each year, it seems reasonable to assume that the exposure error is Berkson, and produced no downward bias in the estimated effect [ 31].
Let us assume that the exposure is homogeneous within the municipality; in the absence of intermunicipality commuting, the fraction of deaths among residents of municipality i that are attributable to PM10 depends only on the exposure response curve and the concentration of PM10 in municipality i.
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We assume that the exposures are log-normally distributed, and that they can be adequately modeled by a mixed effects regression model with parameters for exposure levels and for between- and within-worker variance components.
This assumes that the exposure is computed with a default free assumption.
The base wind speed was derived from observations of extremes at 50 anemograph sites, assuming that the exposure of the each site was uniform by direction.
It is important to emphasize that we are assuming that the exposure in Nuevo Leon depends on the emissions of the neighboring states and not its own emissions.
It was assumed that the exposure risk, which is the expected number of accidents for each category of the pedestrians, was in proportion to their presence in the pedestrian population.
The safety of silver amalgam as a dental restorative material has been controversial since its introduction 150 years ago, but until recently it has been assumed that the exposure to mercury from dental amalgam is limited to the acute placement phase.
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