The phrase "assume mutation" is correct and usable in written English.
It can be used in contexts related to genetics, biology, or programming, where one might need to consider or take into account a change or alteration in a sequence or structure.
Example: "In our analysis, we need to assume mutation in the DNA sequence to understand the potential variations in the organism."
Alternatives: "consider mutation" or "take mutation into account".
In these situations, methods that do not assume mutation-equilibrium, such as STRUCTURE, are more appropriate.
For interaction-loss and – adjustment events we assume mutations lead to changes in the binding surface of one protein leading to loss of an interaction or changes in its efficiency.
With an assumed mutation rate of 2.2 × 10−9 per year17 and a generation time of 3 years, the effective population size of dogs at the beginning of the bottleneck is found to be around 8,500 and the effective size of the extant Chinese indigenous dog population to be around 17,000.
Detecting past variations of effective size is also sensible to the assumed mutation model.
Reproduction assumes mutation (in the form of changes to the cloned matrix W) at a rate μ.
Genotype data from multiple affected individuals were examined for shared blocks of homozygosity assuming mutation and locus homogeneity.
Simulating bottlenecks led to similar biases for ancient population sizes, but estimates of current population sizes were only weakly sensitive to the assumed mutation model.
Although the assumed mutation rate was calibrated for D-loop in Nyctalus noctula, it was also used to estimate population expansion times for M. schreibersii [ 11, 12, 14].
%sensitivity = true positive/ true positive + false negative); %false positive rate = false positive/total number of sample analysed; assuming Mutation Surveyor® analyses are 100% correct.
The estimate of splitting time is highly dependent on the assumed mutation rate, and it would require only a slightly lower mutation rate, 1.5 × 10-4, for the 90% credible interval for splitting time to encompass 8,000 years.
