Exact(22)
Conditional analyses to examine specific SNP associations were performed using PLINK by specifying the associated SNP as a covariate along with the previously mentioned covariates in the linear regression model.
Statistical associations were performed using SAS 9.1 (SAS institute, Cary NC).
Analyses of associations were performed using linear regression models with abnormal MPI as dependent variable.
Single marker associations were performed using regression models including relevant covariates in an additive model (dd = 0, Dd = 1 and DD = 2, where D = minor allele and d = major allele).
In silico analyses for detecting significant GO associations were performed using a Wilcoxon Rank test [ 21].
Analyses of intercorrelations and associations were performed using multivariate linear regression analysis.
Similar(38)
Testing for single marker associations was performed using PLINK software (http://pngu.mgh.harvard.edu/~purcell/plink/) [16] version 0.99q.
Additional redundancy removal and visualization of significant associations was performed using the web tool REViGO [ 22].
Validation of SNPs with significant associations was performed using mammographic density data from two other studies.
Statistical analysis of associations was performed using SAS 9.1 software (SAS Institute, Inc .. Survival curves were plotted using R statistical software, version 2.15.0 (http://www.r-project.org/).org/
Test of bivariate association were performed using Mann Whitney U test and chi square test.
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