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KATZ was successfully applied to predict social associations based on a social network [ 60].
In order to extract the associations between symptoms and genes, we first built symptom-disease associations based on a large number of medical literatures in PubMed [ 25] and the Medical Subject Headings (MeSH).
For BPA, estimates suggested an inverse U-shape association: birth weight increased by 169 g (95% CI: 14, 324) in the second BPA concentration tertile and by 85 g (95% CI: –62, 233) in the third concentration tertile, compared with the first [ Table 3; see also Supplemental Material, Figure 2 (http://dx.doi.org/10.1289/ehp.1103634) for associations based on a restricted cubic spline model].
After correction of the p-values by the Bonferroni method, some large and significant values of the two LD measurements (D' and r) were found both between unlinked and linked markers, preventing any distinction between associations based on a physical link between markers and those created by the structure.
Indeed, the precision of the effect size estimates is also better for the GRS30 when examining the associations based on a per unit increase in the GRS, further supporting the likelihood that the greater number of SNPs accounts for a greater proportion of the phenotypic variance.
The excess for bus or truck drivers was modest but was based on a large number of subjects; moderate to strong associations (based on a few subjects) were observed for several other occupations, including leather tanners and processors, glass workers, and welders.
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Symons et al. [ 12] found that associations based on an 8-hour lagged exposure period were stronger than associations based on 24-hour lagged exposure.
It recommended that officers or employees who are armed take a 40- to 60-hour training course to be developed by the rifle association based on a model the task force has designed.
This study explores such an association based on a combined understanding of customer Cyber (online), Physical, and (some aspects of) Social (CPS) behaviour, at the conjunction of corresponding CPS spaces.
In addition, MVL was not a confounder in the association based on a less than 10% change in the effect estimates after adjustment for MVL (%ln(CoRR) = 6.7%) and because MVL was not associated with CCR5 expression (β = 0.02, 95% CI = −0.35, 0.39).
The multi-SNP analysis aims to test association based on a SNP set, usually defined based on biological knowledge such as gene or pathway, which may contain only a portion of SNPs with effects on the disease.
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