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There was no association of the polymorphism with IRSA in Slovenian women.
However, no statistically significant association of the polymorphism of HCRTR2 rs2653349 with CH was found in several case-control studies in Denmark, Sweden and the UK populations.
Recently,four studies have been conducted to investigate the association of the polymorphism of the human CLOCK gene (rs1801260) with CH,however, no consistent evidence for association of CLOCK with CH was observed yet [24, 27 29].
In the pooled cohort from Stuttgart and Aachen we found a significant association of the polymorphism rs9514089 with gallstone disease (p = 0.00767, OR = 2.04).
We applied a Cox proportional hazards model to study the association of the polymorphism with acute myocardial infarction (AMI) (n = 71) and CHD.
Furthermore, there was no significant association of the polymorphism with plasma vitamin A levels.
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We tested the association of the polymorphisms with type 2 diabetes by using logistic regression.
Multivariate linear regression was used to test the association of the polymorphisms with quantitative traits.
The association of the polymorphisms with the risk for HBV infection or chronic infection was estimated using multiple logistic regression.
Furthermore, we also examined the association of the polymorphisms with clinical characteristics including age at onset, symptoms, and therapeutic effects.
By comparison analysis of genotype distributions, however, we were able to detect association of the polymorphisms with T1D.
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