A critical problem in making use of these sequenced and associated experimental data is the assignment of functional information.
An analysis of the coverage of genome-wide abundance datasets (figure 5) indicates that more than half of all genes (~54%) now have associated experimental data for protein abundance, protein half-life, and mRNA abundance.
Of the 1158 reactions in iRsp1095, 1,049 (90.6%) have gene-protein-reaction (GPR) assignments, with 203 of these having associated experimental data, while 958.2.2%) of the reactions without GPR assignments correspond to place holder reactions for which a putative gene could not be assigned.
The variable internal air temperature can be associated with experimental data.
The validation of rate constants of hydrogen-related reactions can be complicated by uncertainties associated with experimental data caused by the high reactivity and diffusivity of hydrogen.
Results from parametric studies not associated with experimental data showed that at stoichiometric conditions the flame temperature, flame velocity and strain rate are not sensitive to the pressure, although flames become increasingly thinner with increasing pressure and the yield of the unsteady light species is different.
Selected detected topological perturbation effects that could not be associated with experimental data.
For example, it is clear that all HTS assays contain certain noise associated with experimental data.
These curated metabolites are associated with experimental data in the repository, enabling links between chemical structures, raw metabolomics data and biological context to be derived.
Even with so much uncertainties, associated to experimental data, modeling development and some unknown initial conditions, it has been shown that it is possible to fit and/or improve model predictions with parameters identifiability procedures.
