Following a major expansion in 2003, a suite of rooms, used as accommodation by Churchill, his wife and close associates, was added to the museum.
For each bait protein, TRF1, TRF2, and POT1, the MS-identified putative associating partners were added as nodes and color-coded based on the frequency of identification (i.e. TIN2, 7 out of 8, green) for quick reference to the prevalence of the identification.
In addition, genes that distinguish lobular from ductal carcinomas [ 12], and cell cycle associated genes were added to the chip to enable other types of classification.
The L. major iAC560 metabolic network reconstruction included 560 genes (6.7% of the genome) and an additional 103 predicted gene associated reactions that were added for proper functioning of the computational model.
To assess the extent to which components of the metabolic syndrome drive the association with depressive symptoms, we calculated the percent attenuation in the metabolic syndrome depressive symptoms association after the components separately associated with depressive symptoms were added to the model.
Treatment cost increased even further when indirect costs associated with lost productivity were added.
Necessary reactions, which could not have previously been included in the models as they did not have associated enzymes or genes, were added at this point.
In a second model, adverse working conditions that were negatively associated with social class were added as potential confounders or mediators.
In order to ensure accurate annotation of the bleeding and platelet phenotype, 80 terms and associated is-a relationships were added to HPO [ 17], in parallel with development of hpoPlot, a new free software tool that summarises HPO codes of a set of cases, released on the Comprehensive R Archive Network [ 22].
Other variables associated in the bivariate analyses were added one at a time to the base model.
