Chávez's associates were distinguished mostly by their loyalty, and Maduro was perhaps the most loyal of them all.
The contribution of cross-priming versus direct priming in immunity to such intracellular pathogens in vivo is therefore not well established owing to difficulties associated with distinguishing these mechanisms of initiating cellular immune responses.
The earliest SNP discovery and validation studies in white clover represent a good illustration of the problems associated with distinguishing these two types of variation.
However, interpretation of these studies is complicated by difficulties associated with distinguishing the biologically inactive, latent form of TGF-β1 from its activated form.
To date, the cellular biology of enteroendocrine cells, because of their low density (<1%) within the intestinal epithelium and problems associated with distinguishing them from their enterocyte neighbors, has largely been investigated using cell lines.
Ingenuity pathway analysis (IPA) was performed on the set of 204 differentially expressed genes, including their fold change values, in order to identify the most significantly altered gene networks, and the associated functions distinguishing the two groups.
The analytical challenges associated with distinguishing the multiple closely related sterol intermediates in each pathway, and interpreting the complex patterns of isotope enrichment generated by in vivo labeling have been major obstacles to in vivo studies of the Bloch and K R pathways.
To this point, note that the current associated with dopamine was distinguished from current associated with changes in pH (the major interference) by using principle component regression before further statistical analysis.
In the Lower and Middle Palaeolithic, independent settlement units can be distinguished associated with watercourses, whereas the Upper Palaeolithic occupation was concentrated mainly on the eastern promontories of the Krumlov Forest where many stations overlap in space, and a number exhibit evidence of repeated settlement activity.
Additionally, interferon signaling and interferon regulatory pathways (associated with spinal nociception) distinguished between the pain groups, and dendritic cell maturation (associated with mood) delineated between the catastrophizing groups [ 50].
