Microsatellites have been associated with various functional roles such as their possible role in the regulation of promoters, transcription and translation, and these sequence repeats have been credited with evolutionary importance.
CFS is associated with various functional limitations both for work and social life, and assessment of functional ability including sickness abscence is necessary in medical and vocational rehabilitation [ 42].
Recently, Ernst et al. [ 20] applied a multivariate hidden Markov model (HMM) to ChIP-Seq data of 9 histone modifications to infer chromatin modification states associated with various types of functional DNA elements, including enhancers.
According to the European Society of Cardiology (ESC), anemia is associated with various symptoms, worsened functional status, increased risk for CHF, increased hospitalization, and decreased survival; thus, it needs to be diagnosed and managed [ 10].
Those with PTSD symptoms above the cutoff level applied also reported difficulties in performing usual activities, which is in line with both DSM-IV criteria for PTSD [ 29] and other studies [ 30, 31] showing that PTSD is associated with various types of functional impairments.
There are indications that some de novo non-synonymous substitutions could be associated with various intellectual disabilities but the functional impact of these mutations is not well understood [ 45].
Each topic introduced in the present paper serves as a representative of a larger class of interesting problems that arise frequently in many applications such as design tasks, functional optimization associated with various variational formulations, or a number of problems linked to image evaluation.
Post-traumatic stress disorder (PTSD) is associated with various adverse health effects, including reduced functional health and quality of life. 1 2 3 4 5 6 7 8 9 Individuals with PTSD also report more physical symptoms and comorbidities than those without PTSD.
Falls are a leading cause of morbidity and mortality in older people and are associated with various negative health outcomes including fracture, functional decline, fear of falling, loss of confidence, and reduced quality of life [ 2- 6].
The mitochondrion is a multi-functional organelle associated with various diseases including PBC.
Functional annotation using Biomart against the dog genome and non-redundant database identified 36 genes to be associated with various important biological and molecular functions (Additional file 4: Table S3).
