This agrees with the observation that housekeeping genes in mice and human evolve more slowly than tissue-specific genes (Zhang and Li 2004), which can also be associated with the increased breadth of expression of such genes compared with tissue-specific genes (Park and Choi 2010).
As pointed out by Devlin et al. (2006), there are limitations and difficulties associated with collecting the breadth of empirical data required to accurately represent the full range of genotype by environment interactions affecting fitness-related life history traits in the wild.
Beyond the details of these fascinating cases, what emerges is the problem associated with the depth and breadth of the molecular gaze that informs current biology, with its skyrocketing ability to reveal more and more minute details but also with the attending challenge to define thresholds of epistemic significance for each of them (Nowotny and Testa, 2011).
The observed genetic differentiation of C. miliaris at Easter Island could be related to the geographic isolation of C. miliaris at Easter Island, the world's most isolated oceanic island, or associated with the increased dietary breadth of the Easter Island population.
While the importance of locus-specific motifs in the regulation of gene expression is highly recognized, it is becoming clear that some features of gene sequences themselves (referred to as 'genomic traits' henceforth) are associated with the levels and breadths of gene expression.
Two of the most notable of these types of studies involved comparisons of the gut microbiota of obese and lean mice (Turnbaugh et al., 2006) and the identification of large niche breadth associated with the use of a range of different carbon compounds in the coastal ocean (Mou et al., 2008).
In contrast, for radical innovators external search depth (rather than breadth) is associated with the use of formal appropriation mechanisms.
In this study, the breadth of IAN lateralization was not associated with the occurrence of ND significantly.
For incremental innovators, external search breadth (rather than depth) is associated with the use of both formal and informal appropriation mechanisms.
We analyzed structural features of PK genes associated with breadth of expression (defined as the number of tissues where a gene is expressed).
