Exact(10)
Using the yeast cytosine deaminase (CD)/5-fluorocytosine (5-FC) GDEPT system, I employ two separate strategies to mediate the challenges associated with targeted gene delivery.
Patients with EMD at diagnosis or during disease course were associated with targeted drug resistance.
Off-target effects associated with targeted therapies are often attributed to crosstalk, which refers to inter-pathway molecular interactions arising because of explicit regulatory feedback connections between two pathways or because two pathways share one or more molecular components.
In this review, we aim to assess the incidence of cardiac adverse events associated with targeted therapies designed to block HER2 and angiogenic pathways.
Huo, L. & Scarpulla, R. C. Mitochondrial DNA instability and peri-implantation lethality associated with targeted disruption of nuclear respiratory factor 1 in mice.
The aim of this study was to report cases of medication-related osteonecrosis of the jaws (MRONJ) associated with targeted therapy (TT) with or without concomitant antiresorptive treatment, among the Copenhagen ONJ cohort, which includes all consecutive cases of MRONJ seen in Copenhagen.
Similar(50)
However, the light-power requirements associated with targeting large numbers of individually specified cells can be a disadvantage.
Mellor, H. R., Bell, A. R., Valentin, J. P. & Roberts, R. R. Cardiotoxicity associated with targeting kinase pathways in cancer.
How do the positive effects of food aid that's well targeted net out versus the negative effects that are primarily associated with targeting errors?
This is due, in part, to experimental difficulties associated with targeting mtDNA for damage, while sparing nuclear DNA.
Because of the challenges associated with targeting the BCL-2 family of proteins in general and MCL1 in particular, scientists have been forced to devise new strategies to design small molecule BH3-mimetics.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com