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Given the methodological challenges associated with ascertaining traditional clinical effectiveness data in the context of genetic diagnosis, a much-needed evidence base, reflecting on utility in the form of clinical action or altered medical recommendations is beginning to emerge in the pediatric context.
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We examined whether children's increased lifetime exposure to black carbon (BC), a marker of traffic-related particles from gasoline- and especially diesel-powered motor vehicles, was associated with attention ascertained at 7 14 years of age in a birth cohort based in Boston, Massachusetts, that was followed prospectively.
Contrary to this finding, a larger GWAS study aimed at identifying genomic loci associated with NAFLD as ascertained by CT scanning did not find the TRIB1 locus to be one of the significantly associated genes [ 18].
The purpose of this study was to assess knowledge of and attitudes about NHBDs among EMS personnel, evaluate the extent to which knowledge and personal experience with organ donation is associated with attitude, and ascertain the effectiveness of an intervention designed to teach EMS professionals about NHBDs.
The Framework approach was used to analyse data and identify themes associated with prompt return, ascertained from Blood Service records.
The objectives of this study were to determine how effectively warfarin was administered to a cohort of residents in long-term care facilities, to identify the proportion of residents prescribed warfarin-interacting drugs and to ascertain factors associated with poor INR control.
The study of neuronal activity using functional neuro-imaging techniques provides the opportunity to improve understanding of the neuropathological processes associated with schizophrenia and to ascertain differences in the degree, profile and specificity of possible impairments in this group.
After excluding all loci previously reported to be associated with human height, we ascertained 12 genetic variants with P < 5 × 10−6 (Fig. 2 and Supplementary Material, Table S2) for further analysis.
In a longitudinal study of asthmatics by Delfino et al. (2003), daily concentrations of EC, which is similar to BC, were associated with daily respiratory symptoms ascertained from diaries, and same-day averages were more strongly associated with symptoms, compared with previous-day averages.
The definitive phage type 104 (DT104), which has often been associated with multiple-antibiotic-resistant strains with ascertained zoonotic potential and, in many countries, has increased over the past two decades [ 5], does not seem to be widely spread in water buffalo.
To ascertain factors associated with corneal incision contracture (wound burn) secondary to phacoemulsification in the United States and Canada.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com