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In addition, the data confirm that HER-2 overexpression is associated with a worst prognostic in human breast tumors.
That is, the valuation might be affected by prior belief associated with a worst health condition or an emotional response to the hearing of 'all-worst'.
We previously observed that higher levels of Dock1 expression are associated with a worst prognosis in basal and HER2-positive breast cancer patients and showed that the HER2 oncogene uses Dock1 to promote breast cancer progression.
Recent work on breast cancer patients has suggested that MMP-2 negativity may be linked with a favourable prognosis in node-negative breast carcinoma (Hirvonen et al, 2003) and that high activity levels of plasma MMP-9 in breast cancer patients are associated with a worst overall survival rate (Ranuncolo et al, 2003).
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Yet, as the Wall Street Journal reports, there is not enough commercial insurance coverage in the world to adequately cover the costs that would be associated with a worst-case oil train derailment in a major city like Seattle.
The maximum level of RISR represents the worst reaction associated with a given intervention or no intervention at all.
The increased clonal diversity that results from genetic instability is associated with a higher risk of progression [ 12], worst survival [ 13] and resistance to chemotherapy [ 14].
It is therefore necessary to utilize the best methods to study worst-case scenarios associated with a process and/or plant.
We apply this computational method to bound the worst case load associated with an ensemble of random boundary loads given by a second order random process.
From this, the general trend of polypharmacy having worse outcomes is replicated, and clozapine monotherapy is again associated with (at worst) being a member of the average improvement category on each mental state variable, and at best abnormal belief, perception and speech and thought domains show improvement in the above average category.
Moreover, this study highlighted that a high Charlson score (⩾3) was associated with the worst survival, suggesting that a comprehensive geriatric assessment, specifically looking at the type and number of the comorbidities, was mandatory in order to select the patients who may take advantage from a potentially active treatment (Frasci, 2002).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com