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Enhanced efficacy is also associated with a slight decrease in drug toxicity.
In a retrospective population-based cohort study, metformin was associated with a slight decrease in cardiovascular mortality.
In the present study, circumcision before the age of 1 year appeared to be associated with a slight decrease in prostate cancer risk.
ITF prebiotics also decreased Bacteroides intestinalis, Bacteroides vulgatus and Propionibacterium, an effect associated with a slight decrease in fat mass and with plasma lactate and phosphatidylcholine levels.
In animal experiments, tenofovir was not found to have any maternal toxicity but fetal growth was lowered by 13% versus controls and was associated with a slight decrease in bone density.
The increase in AR protein was not due to an increase in mRNA but was associated with a slight decrease in electrophoretic mobility, consistent with post-translation modification (e.g., phosphorylation).
Similar(52)
Among males, a 1-SD increase in maternal patella lead was associated with a slight decrease of 13.6 g by 48 months of age (95% CI, –97.9 to 70.8 g).
Another remarkable result is the slight increase in the synaptic weight of PGA, associated with a slight decrease of the velocity contrast synaptic weight, which are both consistent and related to the nonlinear site response, which lowers the amplification at high PGA, especially for soft soils with low velocities (and high velocity contrast).
For example, in a double-blind placebo-controlled trial in obese women, feeding 16 g/d inulin and oligofructose (50/50) vs. placebo (maltodextrin) for 3 months decreased Bacteroides, which was associated with a slight reduction in fat mass [ 20].
Higher intakes (401 800 and > 800) were associated with either a slight decrease in occurrence (OR = 0.8 for 401 800) or no effect (OR = 1.0 for > 800).
24 On the patient level, discontinuation of rosiglitazone was associated with a slight overall decrease in the mean level of glycated haemoglobin.
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