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Trinucleotide (and hexanucleotide) motifs are expected to predominate in the population of CDS microsatellites, as variation in their repeat number is not associated with a frame shift event [ 29].
Mutations predicted to result in protein truncation, i.e. nonsense mutations, short deletion/insertion mutations lying within one exon associated with a frame shift, mutations involving nucleotides ±1 and ±2 within splicing junctions and large genomic rearrangements, are highly likely to impair the MMR function and are definitely classified as causing Lynch syndrome without additional information.
These different variations were predicted to result in protein truncation (nonsense mutations, insertions or deletions associated with a frame shift, mutations involving nucleotides ±1 and ±2 within splicing junctions) in 171 (40%) occasions on MLH1, 199 (44%) on MSH2 and 97 (33%) on MSH6.
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When dealing with wheel-rail interactions for a high-speed train using the time domain Green function of a railway track, it would be more reasonable to use the moving Green function associated with a reference frame moving with the train, since observed from this frame wheel/rail forces are stationary.
Note that only about half of the outcomes were associated with an actual monetary reward, which was signaled by a green frame around the outcomes, while the rest was associated with a red frame around the outcome, indicating that subjects did not receive a reward in this trial.
While this unusual condition lasts, the event is not only, as is normally the case, associated with a single frame of reference but "bisociated" with two.
Nodes in the graph are segments which are associated with a particular frame, and the edges in the graph are temporal relationships (links) between segments.
Each exon is associated with a reading frame in which translation is expected to occur.
As the RNA_editing annotations are not directly associated with a reading frame, the use of a "gene" qualifier to assign a certain editing event to a CDS with the same name is encouraged or even mandatory when there are overlapping reading frames present.
The user can identify orphan probes or locate probes by sequence, but since probes are not associated with a defined frame they are currently not linked to O SS. RNA-Seq data are imported as either two WIG files, with coordinates and coverage values for the positive and negative DNA strands, or as a SAM file from which the coordinates and coverage values are computed.
For simplicity, we assumed in this study that the packets associated with a specific video frame share the same importance level, i.e., the DVFI value of that video frame.
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