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RA and T1D are known to share associated variants [28], [29].
Fine scale mapping has not identified any other independently associated variants in the region.
Identifying associated variants is an important first step toward understanding novel aspects of the etiology of disease.
Initial publications for these novel, AD associated variants provided some hypotheses for each of the reported genes.
Clinically associated variants are inherently biased toward dysfunction.
We plan to identify variants associated with medication adverse events and efficacy to determine associated variants.
Similar(38)
We had data on Y402H in 709 cases and 373 controls for whom genotypes on T2-associated variants existed.
Resistance-associated variants (RAVs) can limit the efficacy of DAA therapy and are associated with increased risk for therapy failure.
In this study, we examined the aggregate effects of these IOP-, VCDR-associated variants on glaucoma.
Breakpoint analysis showed that the predominant mechanism of formation of these complex duplication-associated variants was microhomology-mediated repair.
Disease-associated variants may also be acting via effects on gene expression [47].
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