Sentence examples for associated tissue damage from inspiring English sources

Thus, by targeting specific pathways after TLR activation, it is possible to enhance innate defense without the induction of inflammation, hence avoiding its associated tissue damage.

The extreme susceptibility of DBA/2J mice could be due to enhanced viral replication and associated tissue damage or a detrimental immunopathology of the host response, or both.

Gut luminal antigens have attracted great attention, and the current paradigm proposes that interactions of such bacteria with the host's epithelial cells and the mucosal immune system eventually results in continuous microbial antigenic stimulation and associated tissue damage [19].

With regard to the present findings of coordinated induction of the TLR2/6 complex during hypoxia, it remains unclear if such changes in TLR signaling patterns represent a protective host-defense mechanism or can further exacerbate infection and inflammation associated tissue damage.

Controlling the inflammatory response resulting from an IAV infection is of great significance in reducing associated tissue damage.

It becomes increasingly clear that TLR mediated meningeal inflammation is a pivotal factor for meningitis associated tissue damage [ 8].

This may suggest that inflammation-associated tissue damage contributing to lifespan reduction is carried through complete metamorphosis.

Excess production of free radicals causes premature cellular senescence and accelerates age-associated tissue damage in animal models of visceral obesity[31].

The HIF-1 α deficient mice also had much less sepsis-associated tissue damage in different organs as demonstrated by an e.g. significant decrease in levels of liver enzymes (Fig. 1D).

CNS-protective effects (anticonvulsive effects, reduction of stroke-associated tissue damage, inhibition of glioblastoma).

Food-derived AGEs have been shown to promote the aging-associated tissue damage as well [ 49- 52].