Sentence examples for associated substrates from inspiring English sources

Accordingly, efficient methods for characterization of proteases and their associated substrates could enhance our understanding of biological systems, which ultimately may result in new therapeutic strategies.

While our data set of ascomycota strains and the FAEs associated substrates is relatively large, it is still limited as new reactions for this promiscuous enzyme family are discovered through the isolation and biochemical characterization of novel FAEs.

10.7554/eLife.01319.009 Figure 4. RIIα linker length influences basal PKA phosphorylation of associated substrates.

Some may, for instance, target cellulose and cellulose associated substrates (as in Figure 2b) but bifunctional enzymes likely targeting hemicellulose may also be found (several examples in Figure 2c).

In conjunction with altered mitochondrial function and motility, tubulin cytoskeleton alterations may contribute to the accumulation of protein aggregates and autophagic vesicles, and/or associated substrates, as observed in our sPD cybrids model.

Opportunities to innovate may be influenced by the accessibility of associated substrates or social resources which may be seasonal, rare or highly unpredictable in their availability [67], [68].

We found both abdominal quivering and associated substrate-borne vibrations are conserved in other Drosophila species.

However, with DDBP1 its associated substrate ligand is linked to the degradation of a cell cycle inhibitor [ 74], and thus up-regulation of this gene would be expected to increase cell growth.

Using the nomenclature for the canonical VirB/VirD4 T-DNA transfer system of the tumorigenic plant pathogen Agrobacterium tumefaciens, T4SSs are macromolecular assemblies of at least 10 essential components termed VirB2 VirB11, and an associated substrate recognition receptor known as the type IV secretion coupling protein (T4CP) VirD4.

It also promotes anoikis (cell death secondary to the deregulation of focal adhesion complexes and loss of cell attachment to the extracellular matrix) by deregulating the focal adhesion assembly protein CRK-associated substrate P130CAS [ 15].

Conversely, potential toxicities of BACE1 inhibition may be less associated with substrates that are primarily cleaved by ADAM proteases over BACE1.