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These proposed events occurred within and between genes from three separate families (' brain- expressed X-linked' [ BEX], WWbp5-like X-linked [ WEX] and G-protein-coupled receptor- associated sorting protein [ GASP]), all of which contain single protein-coding exons.
These concerted evolution events occurred within and between genes from three separate protein families (' brain- expressed X-linked' [ BEX], WWbp5-like X-linked [ WEX] and G-protein-coupled receptor- associated sorting protein [ GASP]), which often are expressed in mammalian brains and associated with receptor mediated signalling and apoptosis.
In this study, we used wild type (WT) and G protein coupled receptor associated sorting protein-1 (GASP-1) knock out (KO) mice to assess molecular changes that accompany cocaine sensitization.
GASP-1 and -2 are G-protein-coupled receptor (GPCR) associated sorting proteins (GASPs) which bind to the COOH-termini of various GPCRs and modulate their endocytic sorting to lysosomes [ 20, 21].
Disabled-2 (Dab2) is a clathrin associated sorting protein (CLASP) that also mediates clathrin assembly and cargo selection.
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However, given the low frequency of IAV mRNA positive cells in the LN, and the technical difficulty associated with sorting very rare populations of DC, this could also be an artifact resulting from cell sorting contamination.
The domain architecture of CCU75320 resembles human RGS-PX1, a presumably bifunctional protein in which the RGS domain is associated with sorting nexin features, thereby possibly linking G protein regulation to vesicular trafficking [ 28].
At this time it was also recognized that the mechanism for segregation of cargo proteins (either soluble or membrane associated), or sorting into a particular pathway was an important issue, as was the identification of the precise location for the initiation of the sorting process.
Describes how Robbin and associates sorted the 1970 Census data by Zip Code, noting a thousand variables for each of the nearly 35,600 Codes.
SUM149PT cells were fluorescence associated cell sorted after immunolabeling with CD49f and Epcam as previously described [ 6].
For high purity sorts required for metabolite profile or protein isolation, neutrophils were further purified by fluorescent associated cell sorting by Ly6G+, purities obtained were >95%.
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