Exact(1)
Indeed, intriguing questions still remain as to whether acute or continuous treatment with Met can impact seizure frequency, other epileptiform activity patterns, progression of epilepsy, or sustain the associated rescue of memory deficits with TLE.
Similar(59)
This effect was not associated with rescue of DNA damage signaling but rather with a significant reversal of the mitochondrial abnormalities.
Recovery of ascl1b expression in VPA-treated hdac1 s436 or mib mutant embryos is associated with rescue of 5HT neuronal differentiation.
Next, we set out to determine whether mtZFN-dependent shifts in heteroplasmy from CD to wild-type mtDNA were associated with rescue of mitochondrial respiratory function.
With respect to hypertrophy, it is of interest that shPLB treatment was associated with rescue of the phenylephrine-induced miRNA-133 depression in NRCMs and higher levels in rat hearts on shPLB treatment.
None of the RNAi vectors changed miRNA-1 levels in NRCMs, but interestingly, shPLB treatment was instead associated with rescue of the miRNA-1 depression induced by phenylephrine in these cells, and rat hearts that underwent shPLB therapy had higher miRNA levels than controls.
By contrast, the chloroplasts of WT and line #11 contained well-stacked grana thylakoids without plastoglobules (Fig. 2a and c), suggesting that the recovery of the leaf phenotype in OPAO plants is closely associated with the rescue of chloroplast development.
Weak binding of the mouse FCHo1 APA fragment to AP2 (See also Figure 7 figure supplement 2 ) was associated with weak rescue of fcho-1 mutants in (A ).
TG2 inhibition normalizes these 'metabolic' genes and induces resistance of HD cells to mitochondrial toxins; unexpectedly this resistance was not associated with the rescue of abnormal mitochondrial bioenergetics in HD.
Strikingly, the positive effect of βCD-mediated cholesterol removal on palmitate-impaired GLUT4 translocation and glucose transport (Fig. 3c, d) was not associated with a rescue of the palmitate-induced defect in Akt2 phosphorylation (Fig. 5).
Correlation of the expression of the overlapping 121 genes between the two comparisons confirms that most of these (116 genes; 77% of total genes changed with J147) are indeed associated with a rescue of age-related changes in gene expression (Fig. 7 C).
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