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The persistent CMV associated inflammatory response outlined here is also notable for its magnitude.
The associated inflammatory response to an unresolved infection may be partly responsible for the observed hypotension and organ failure operating through an alternative mechanism.
The wound healing process restores tissue integrity and repairs the damage induced by the initial injury and by the associated inflammatory response.
These patterns are deciphered by receptors (pattern recognition receptors, PRRs; e.g. CR3) that control phagocytosis and associated inflammatory response depending on the meaning of these signals.
Although monofilament absorbable sutures e.g. polyglyconate co-polymer Maxon (Covidien, Mansfield, MA, USA) are broken down over 6 weeks, which may potentially avoid stress shielding (Table 1), the associated inflammatory response may actually weaken the healing tendon predisposing to re-rupture at a key phase in the rehabilitation process.
In addition, the presence of Schistosoma coinfection during uncomplicated P. falciparum malaria unbalances the regulation of the associated inflammatory response [15].
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Pathophysiologically, exposure to CARDS toxin and the associated inflammatory responses in the lungs could account for the changes observed in pulmonary function after infection.
The infections and the associated inflammatory responses are the most important causes of morbidity and mortality in CF patients today.
We speculated that inducing very severe lung damage with multiple doses of elastase interfered with virus infection and associated inflammatory responses, as previously reported [ 19].
In addition, bacterial or viral infections and the associated inflammatory responses have a significant effect on HSCs and thus likely also on their niches [ 79].
Chronic infection and associated inflammatory responses lead to progressive loss of lung function and respiratory failure (Callaghan and McClean 2012; Costello et al. 2011).
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