Sentence examples for associated dose from inspiring English sources

Translational PK-PD modeling can support the design of FIH studies by providing estimates of efficacious target exposures, associated dose regimens, and guidance in selection of biomarker and optimal sampling time points for exposure and biomarkers.

The following topics are addressed: (i) assumed properties of an inadvertent drilling intrusion and the determination of the associated dose and expected (mean) dose to the RMEI, (ii) uncertainty and sensitivity analysis results for expected dose to the RMEI, and (iii) the numerical stability of the sampling-based procedure used to estimate expected (mean) dose to the RMEI.

First sign of efficacy, maximum tolerated dose (MTD) and their associated dose level were recorded in each trial.

In addition, this approach did not include features such as model-based descriptions key to dose-limiting toxicities and associated dose reductions, and biomarkers for disease progression.

This figure depicts for each simulated individual the expected costs and expected efficacy, taking into consideration simulated values derived from toxicity and efficacy models and associated dose reductions, in comparison with the base scenario.

In addition to the studies in the 3-D corneal cultures, we conducted a 1-year corneal pachymetry study in monkeys that demonstrated no effects of suprapharmacologic doses (67 times the recommended clinical dose of latanoprost and 4 times the associated dose of BAC) on corneal thickness.

Smart pumps can help to prevent infusion-related programming errors, thanks to associated dose-limiting software known as "drug library".

Moreover, the lower the value of M, the less precise the estimates of the associated doses will be.

It linked the radiobiology associated with dose delivery and viewed dose from a purely physical model of energy deposition (Moawad 2010).

The clinical use of doxorubicin is associated with dose limiting cardiotoxicity.

The γH2AX assay circumvents confounding problems that may be associated with dose.