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However, self-disturbances have not been extensively investigated, in part, due to the subjective nature of such processes, and the associated difficulty of studying these phenomena using empirical methodology.
Further, as nodes are removed from the network, the identity of the driver nodes may change but, more importantly to our application, the number of driver nodes – and the associated difficulty of controlling the network – may remain fixed or also change.
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Generating such scientific evidence is important in light of today's donor organ crisis and the associated difficulties of equitable resource allocation.
Hence, our BN model focuses only on source level hypotheses, ignoring the offence level hypotheses and the associated difficulties of modelling factors like opportunity, motive and intent.
The associated difficulties of introducing obesity into conversation were discussed in great detail.
Epistatic variance provides other associated difficulties of potential confounding and estimation.
Owing to their occurrence during early development and associated difficulties of diagnosis and remediation, primary prevention is the optimal therapeutic approach.
Reports of community based services available for this group of patients revealed the intricacies of service provision (multiple programs and providers, variation in eligibility criteria etc)., and associated difficulties of communication and coordination both within and between services.
The poor diagnostic specificity of PCR and the associated difficulties for clinical interpretation of test results have been highlighted for other viral pathogens [ 10, 11].
A major challenge in planning analyses assessing causal pathways is the extent to which obstetric risk factors are linked, and the associated difficulty in analysis of sorting out the impact of method of birth (as the 'exposure of main interest') from other exposure and treatment effects.
The ethical significance of the identified impacts was predicted based on the associated difficulties to meet these criteria.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com