Sentence examples for associated cell apoptosis from inspiring English sources
However, as a major contributor to cancer survival, whether mitochondrial uncoupling could exert an anti-apoptotic influence on TPA-induced skin tumor promotion, and the precise mechanisms by which mitochondrial uncoupling may interact with p53 mitochondrial translocation and associated cell apoptosis pathways are not known and have been explored here.
We showed that MTX induced ROS production in MTX-sensitive U2OS cells while ERR α effectively blocked the ROS production and ROS associated cell apoptosis.
Although the VCP-centered ERAD pathway is concurrently activated to extract unfolded proteins from the ER to mitigate the elevated ER stress, ER stress-associated cell apoptosis is eventually enforced in the target cells.
P-glycoprotein functional inhibition and mitochondria-associated cell apoptosis induced by TPGS were thought to play an important role in overcoming the multidrug resistance.
The Ca2+ release from the ER is likely to be crucial for relaying I-Trp-induced ER stress-associated cell apoptosis, as the elevated Ca2+ levels via the capacitative Ca2+ entry model are required to trigger mitochondrial perturbation, cytochrome c release and caspase overactivation.
Hashimoto et al. (Hashimoto et al., 1999) suggested that pathological changes in the meniscus are associated with cell apoptosis, and observed that the percentage of apoptotic cells correlated with the severity of tissue destruction.
Double Strand DNA breaks, which are often associated with cell apoptosis, were detected using the "In Situ Cell Death" Detection kit (Roche; Mannheim, Germany) (TUNEL method) performed according to the manufacturer's instructions.
ROS generation was usually associated with cell apoptosis.
Conversely, the activities of PP2A and PP1 have been associated with cell apoptosis.
These suggested that the mechanism of tumor inhibition by EAC-B was associated with cell apoptosis.
Cleavage of caspase and PARP is associated with cell apoptosis [ 17].
