Sentence examples for associated aggregation of from inspiring English sources

Myocardial fibers showed loss of cross-striation, pyknotic nuclei and associated aggregation of lymphocytes.

TDP-43 has recently drawn considerable attention because it has been found that hyperphosphorylation-associated aggregation of TDP-43 is a signature of two neurodegenerative diseases: amyotrophic sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP) [ 89, 90].

Importantly, we did not observe any difference in the extent of age-associated aggregation of YFP polyQ35 in hif 1 ia04) mutant animals compared to wild-type controls (Fig. 4B).

We showed that TcdA, in higher concentration, caused dramatic changes in cell morphlogy as assessed by AFM associated with significant decrease in both cell volume and area and increase in cell height, as a result of shrinkage of the cell associated with aggregation of cellular material around the nucleus.

We found that dying hepatocytes in the liver of obese Sesn2−/− mice were frequently associated with aggregation of dense-nucleated cells (Supplementary Fig. 9a), most of which were identified as F4/80-positive macrophages (Supplementary Fig. 9b).

PD is associated with aggregation of alpha-synuclein and death of dopaminergic neurons leading to motor decline.

Alzheimer's disease is the most common neurodegenerative disease, associated with aggregation of amyloid-β (Aβ) peptides.

Animals expressing high levels of γ-synuclein develop severe and fatal neurological disease associated with aggregation of the overexpressed protein and its deposition in cytoplasmic and axonal lesions.

Double immunostaining results revealed that the reduction in dynein level was associated with aggregation of A53T a-synuclein in the striatum.

Remarkably, only the first, low Tm transition was detected by DSF, whereas the second appears to be lost due to baseline decay and distortion associated with aggregation of the protein following the unfolding of the first domain [ 37].

This neurodegeneration is firmly associated with aggregation of the 40- to 42-amino acid amyloid beta (Aβ) peptide into senile plaques, phosphorylation and aggregation of tau proteins that form neurofibrillary tangles, and microglial activation that may be a protective response or contribute to the neuronal dysfunction and damage [ 2].