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It can be inferred that the C-terminal Ig-like structure also physically associate with the active site of the catalytic domain of PglA and hampered the thermal activity and stability of the enzyme.
We now provide direct experimental evidence that the pseudosubstrate prototope can associate with the active site.
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Not all promoters associated with the active H3K4me3 mark are actively transcribed [30].
Moral virtues belong to the appetites and desires of the sensory soul — the part obviously associated with the active political life, when its activities are brought under the guidance and control of excellent practical thought and judgment.
Thus, catalytic-core histaminylation increases the GTP hydrolysis activity, and stabilizes protein interactions associated with the active state of Cdc42 and Gαo1.
Furthermore, immunoprecipitation and cell fractionation analyses show that HOT1 associates with the active telomerase complex and promotes chromatin association of telomerase.
We wished to carry out a detailed scan across the entire H19/ Igf2 region to determine the parental-specific chromatin loop organization associated with the active transcriptional status as well as repression mediated by enhancer-blocking activity or methylation.
NNRTIs bind in a region not associated with the active site of the enzyme.
NNRTIs bind to a region that is not associated with the active site of the enzyme.
Despite the highly flexible 'personality' of EI, the ligand remains tightly associated with the active site residues.
In particular, they are associated with the active maintenance of stimuli in verbal working memory (Weiss and Rappelsberger, 2000).
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