The phrase "associate with high affinity" is correct and usable in written English.
It is typically used in scientific or technical contexts, particularly in fields like biochemistry or pharmacology, to describe a strong interaction between molecules or compounds.
Example: "The drug was found to associate with high affinity to the target receptor, leading to enhanced therapeutic effects."
Alternatives: "bind with strong affinity" or "interact with high specificity."
The existence of cell surface heparanase receptor(s) is supported by binding experiment, reinforcing the notion that while HSPGs serve as low affinity, high abundant binding sites, heparanase also associates with high affinity, low abundant cell surface receptor(s) [67].
The decrease in the levels of GSH following exposure to arsenic has been found to be associated with high affinity of arsenic with GSH [ 51].
Specifically, quetiapine is associated with high affinity at the H1 receptor where it acts as an antagonist ; this mechanism is associated with sedation in both animal models and human studies.
Much of the total cellular copper is associated with high affinity binding proteins, and what is considered labile copper is effectively buffered by a plethora of cellular ligands that minimize free copper ions.
This mechanism generally mediates the assembly of meta-stable signalling platforms whose subunits associate with higher affinity than the sum of the individual interactions, which usually are relatively weak (5).
Kaiso belongs to a unique family of transcription factors that can associate selectively, and with high affinity, to methylated CpG DNA via zinc finger domains [29].
The mutants, AAA, T613D, T616D, and the truncated form of the transporter, Δ6, which show decreased densities on the plasma membrane in response to 5HT stimulation, associated with phosphovimentin with high affinity (Fig. 7D).
Energy logos for AncSR1 (left) and AncSR1+RH (right) show the effects of nucleotide states on binding energy relative to the average across all REs tested; states with ΔΔGdissociation > 0 are associated with higher affinity binding.
However, under these conditions RNA binding proteins are free to dissociate from their endogenous RNA targets and re-associate with higher affinity binding sites, thus there is great risk of false discovery [ 6].
Nuc can associate with COX-2 with high affinity and increase the resulting PGE2 generation.
